Use case of BBC pipeline to retrieve purified samples

Material and methods

Objectives

  • Identification of a gene signatures, and associated pathways, describing treatments’ effects

  • Evaluation of differential cell composition due to treatment

Study Design

  • RNA was extracted with kit XXX for 5 donors

  • Donors have been treated wih AAA, BBB, CCC and a Placebo

Statistical analysis

We focus on the comparison between

  • AAA vs Placebo
  • BBB vs Placebo
  • CCC vs Placebo

Differential expression analysis

Enrichment analysis

Immune signatures and Deconvolution analysis

References